Researchers believe organs will soon be printable
A
collaborative study between three universities, led by University of
Missouri-Columbia biological physics professor Gabor Forgacs, claims
that it will soon be possible to print organs out using bio-ink and
bio-paper, and so far the study has produced tubes similar to blood
vessels and sheets of heart muscle cells.
* Led by University of
Missouri-Columbia biological physics professor Gabor Forgacs and aided
by a $5 million National Science Foundation grant, researchers at three
universities have developed bio-ink and bio-paper that could make
so-called organ printing a reality.
* So far, they’ve made tubes
similar to human blood vessels and sheets of heart muscle cells,
printed in three dimensions on a special printer.
* “I think
this is going to be a biggie,” said Glenn D. Prestwich, the University
of Utah professor who developed the bio-paper.
* “A lot of things are going to be a pain in the butt to print, but I think we can do livers and kidneys as well.”
* Prestwich guessed initial human organ printing may be five or 10 years away.
* Once the stack is the right size — maybe two centimeters’ worth of
sheets, each containing a ring of blots, for a tube resembling a blood
vessel — printing stops.
* The stack is incubated in a bioreactor, where cells fuse with their neighbors in all directions.
* The bio-paper works as a scaffold to support and nurture cells, and
should be eaten away by them or naturally degrade, researchers said.
* Though it can take less than two minutes to print a sheet of
bio-paper with bio-ink, it can take about a week for such a tube to
fuse, Forgacs said.
* It’s currently feasible to print tubes,
Prestwich explained, because the printers output bio-paper in a sort of
ever-ascending spiral, like a Slinky.
* Helen Lu, director of
the Biomaterials and Interface Tissue Engineering Laboratory at
Columbia University, thinks organ printing could eventually work.
* Still, she cautioned that scientists must determine additional
details such as how blood vessels are formed in skin, because simply
implanting them might not be optimal.
Tonernews.com, January 10, 2006. USA